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Forteo

Forteo questions and answers

Learn more about Forteo.

Q: what is the cost for prescription drug Forteo?
I have a prescription for Forteo and even my pharmacist can't give me a price until I order it. I have a Blue cross Blue shield HMO. I don't know if I can afford it.

A: I can only tell you the cash price, but since you have insurance, it will be different. The cost for 3 syringes is about $2,500.

Q: Any suggestions for making daily subcutaneous shots of Forteo less painful.?
Forteo, as you know, is daily treatment for osteoporosis (for 2 years). Any links for online reading will be appreciated. Thanks.

A: I don't know if you already have the delivery pen? Here is a link ...... http://www.forteo.com/secure/hcp/pen.jsp

Q: Do you trust drugs for ostereoporosis like fosamax or forteo? Can we reverse bones brittling?
Do you know natural ways of reversing it?

A: As I know, this drugs are used in treating osteoporosis but it does not show can reverse bones brittling. It help to minimize the process of osteoporosis and help in some absorption of the nutrient like calcium for replacement therapy.

Q: Does anyone know anything about Forteo injections, to treat Osteoporosis and about complications?
I'm concern, about Forteo causing Osteosarcoma. A rare form of bone cancer...

A: well it is possible but uncommon, otherwise forteo is a very promising drug, ensure to repeat the dexa scan in 1-2 years, at the moment forteo is not approved for more than 2 years, good luck

Q: Can a patient with impaired liver function take Forteo safely?
IS THERE A HEPATOLOGIST IN THE HOUSE? Cliffie, no problem - I've seen your "?"s and think well of them.

A: Probably not, because Forteo undergoes extensive hepatic metabolism by the P450 system, which is also the reason that it is not administered orally (though also because GI-peptidases destroy it). So, depending on extent of liver impairment, there may be risk of toxicity if hepatic metabolism is not adequate

Q: Just started Forteo injections. After injecting I have had some blood at the injection site.?
Is seeing some blood at the injection site after injection normal? I have also had clear liquid at the site. Looks like may not be getting all of the drug upon injection. Can someone tell me if this has happened to them!!!

A: I am on Forteo also and it is normal to have a little blood at the injection site. As far as the clear liquid, I would not worry about it. It is just some of the medication coming out. That little bit will not make a difference. I have been on it now for 1 year. I am hoping that when I go in for my next bone scan that it will have made a difference. I wish you luck with yours.

Q: Is forteo available in a pill form?


A: No, it only comes as a liquid that is to be injected. http://www.drugs.com/forteo.html

Q: Drug experience with Forteo?
To everyone who is taking, has taken or knows someone who is taking Forteo for osteoporosis, what are your/their experiences with this drug? It is a daily injectable drug used to treat severe osteoporosis. Have you or anyone you know had any problems with this drug? My doctor has prescribed this, and I'd like to know any adverse side effects before I start taking it.

A: I am making my 3rd attempt with the Forteo this week. It gives me labor pains and extreme nausea. They want me to try to work through the symptoms and give it a longer try this time. The last two times I had chest pains after about the 5th day. I am desperate to get past this pain that has be so inactive.

Q: Forteo drug experience?
To everyone who is taking, has taken or knows someone who is taking Forteo for osteoporosis, what are your/their experiences with this drug? It is a daily injectable drug used to treat severe osteoporosis. Have you or anyone you know had any problems with this drug? My doctor has prescribed this, and I'd like to know any adverse side effects before I start taking it. I'd just like to hear from people who've actually taken it before I pay over $700/mo for it.

A: sounds painful. :) stinks that u have osteo. holy cow $700 a month! stinks for you...... Oh and i hope your knee gets better.

Q: Does FORTEO have any adverse affects on the liver ?


A: i could answer you but i'd rather send you to this wonderful Forteo site that will have professionals answer you for free

Q: Is it advisable for a Pt. with (stage ii) Primary Biliary Cirrhosis to begin a Forteo regimen?
PMedx - has had PBC since 1995; diabetic; osteoporosis Socialx- no illicit drug use, consumption of EtoH, smoking; retired teacher MEDS: Amaryl, Hydrochlorothiazide, K-Lor Also Urso 250, and Synthroid .75mcg

A: This depends on a great many circumstances. This medication is a big inconvenience to begin with, as it is to be injected daily. At any rate, you should consult a hepatologist on this one for sure. That is all I can tell you. Nice job on Pt. History, but I would need more info. to make an honest recommendation. CBC and other test results would be helpful.

Q: what is the best way to build or maintain bone health?
I have taken forteo injections for one year and gotten nothing. Bought a Bowflex thought maybe exercise as I need it anyway. I am 45 and need some help.

A: also use upto 1500 mg of calcium daily as well as 800 international units of vitamin d daily. you can try miacalcin nasal spray, fosamax as well, females can try evistat too. conjunction therapy may carry some more risk of side effects, discuss with your doctor, remember to quit forteo at 2 years

Q: forteo a new drug for bones anyone taking it???????


A: INDICATIONS AND USAGE FORTEO is indicated for the treatment of postmenopausal women with osteoporosis who are at high risk for fracture. These include women with a history of osteoporotic fracture, or who have multiple risk factors for fracture, or who have failed or are intolerant of previous osteoporosis therapy, based upon physician assessment ( see BLACK BOX WARNING ). In postmenopausal women with osteoporosis, FORTEO increases BMD and reduces the risk of vertebral and nonvertebral fractures. FORTEO is indicated to increase bone mass in men with primary or hypogonadal osteoporosis who are at high risk for fracture. These include men with a history of osteoporotic fracture, or who have multiple risk factors for fracture, or who have failed or are intolerant to previous osteoporosis therapy, based upon physician assessment ( see BLACK BOX WARNING ). In men with primary or hypogonadal osteoporosis, FORTEO increases BMD. The effects of FORTEO on risk for fracture in men have not been studied. * FORTEO reduces the risk of vertebral fractures in postmenopausal women with osteoporosis. * FORTEO reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis. * FORTEO increases vertebral and femoral neck BMD in postmenopausal women with osteoporosis and in men with primary or hypogonadal osteoporosis. * The effects of FORTEO on fracture risk have not been studied in men. CONTRAINDICATIONS FORTEO should not be given to patients with hypersensitivity to teriparatide or to any of its excipients. WARNINGS In male and female rats, teriparatide caused an increase in the incidence of osteosarcoma (a malignant bone tumor) that was dependent on dose and treatment duration ( see BLACK BOX WARNING and PRECAUTIONS ; Carcinogenesis ). The following categories of patients have increased baseline risk of osteosarcoma and therefore should not be treated with FORTEO: * Paget's disease of bone. FORTEO should not be given to patients with Paget's disease of bone. Unexplained elevations of alkaline phosphatase may indicate Paget's disease of bone. * Pediatric populations. FORTEO has not been studied in pediatric populations. FORTEO should not be used in pediatric patients or young adults with open epiphyses. * Prior external beam or implant radiation therapy involving the skeleton. FORTEO should not be given to such patients. Patients with bone metastases or a history of skeletal malignancies should be excluded from treatment with FORTEO. Patients with metabolic bone diseases other than osteoporosis should be excluded from treatment with FORTEO. FORTEO has not been studied in patients with pre-existing hypercalcemia. These patients should be excluded from treatment with FORTEO because of the possibility of exacerbating hypercalcemia. PRECAUTIONS General --The safety and efficacy of FORTEO have not been evaluated beyond 2 years of treatment. Consequently, use of the drug for more than 2 years is not recommended. In clinical trials, the frequency of urolithiasis was similar in patients treated with FORTEO and placebo. However, FORTEO has not been studied in patients with active urolithiasis. If active urolithiasis or pre-existing hypercalciuria are suspected, measurement of urinary calcium excretion should be considered. FORTEO should be used with caution in patients with active or recent urolithiasis because of the potential to exacerbate this condition. Hypotension--In short-term clinical pharmacology studies with teriparatide, transient episodes of symptomatic orthostatic hypotension were observed infrequently. Typically, an event began within 4 hours of dosing and spontaneously resolved within a few minutes to a few hours. When transient orthostatic hypotension occurred, it happened within the first several doses, it was relieved by placing the person in a reclining position, and it did not preclude continued treatment. Concomitant treatment with digitalis--In a study of 15 healthy people administered digoxin daily to steady state, a single FORTEO dose did not alter the effect of digoxin on the systolic time interval (from electrocardiographic Q-wave onset to aortic valve closure, a measure of digoxin's calcium-mediated cardiac effect). However, sporadic case reports have suggested that hypercalcemia may predispose patients to digitalis toxicity. Because FORTEO transiently increases serum calcium, FORTEO should be used with caution in patients taking digitalis. Hepatic, renal, and cardiac--Limited information is available to evaluate safety in patients with hepatic, renal, and cardiac disease.

Q: is forteo a phosphate drug?


A: Teriparatide (Forteo®) is a recombinant form of parathyroid hormone, used in the treatment of advanced osteoporosis. It is manufactured and marketed by Eli Lilly and Company. Teriparatide is the portion of human parathyroid hormone (PTH),amino acid sequence 1 through 34 of the complete molecule which contains amino acid sequence 1 to 84. Endogenous PTH is the primary regulator of calcium and phosphate metabolism in bone and kidney. Daily injections of teriparatide stimulate new bone formation leading to increased bone mineral density. Teriparatide is the first FDA approved agent for the treatment of osteoporosis that stimulates new bone formation. Based on the description, I would say it is not a phosphate drug.

Q: Why is parathyroid hormone in osteoporosis?
They have that drug called Forteo which is parathyroid hormone which they give to post menopausal women with osteoporosis. Why in the world would you give them that drug? Why not calcitonin (thyroid hormone)?

A: This was confusing to me too. So, I reviewed some research papers on this to try to understand what is going on (see links below). Apparently, parathyroid hormone and its synthetic analogs have an anabolic effect on bone which appears to be beneficial for patients with osteoporosis. http://www.ncbi.nlm.nih.gov/pubmed/19189037?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum http://www.ncbi.nlm.nih.gov/pubmed/17107220?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=2&log$=relatedarticles&logdbfrom=pubmed Thanks for the interesting question. I learned something. Best wishes.